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Engineered TissuesCellsCustom Services

Custom Services

 

NEW!

For more information of these and other products please go to www.northlandlabs.com
and click on the products tab.

Custom Isolations
Articular Engineering can isolate specific cells from specific tissues. You can either supply us with the tissue, or we can acquire the tissue for you.

 

Large-scale cell production
Articular Engineering can provide services to isolate or expand cell population to provide large cell numbers.

 

Monolayer expansion and cryopresevation
Articular Engineering can provide services to expand and/or cryopreserve cells.

 

Analysis
Articular Engineering can provide testing services for the analysis of ARC™ tissue as well as other samples. All analysis has been optimized for ARC™ tissue and will be performed by a trained cartilage specialist. Analysis includes:

  • Collagen typing

  • Collagen crosslink content (pyridinoline, deoxypyridinoline, hydroxyproline)

  • Sulfated proteoglycan (PG) content

  • Hyaluronan content

  • DNA content

  • Production of frozen or paraffin sections for immunohistochemical methods, Histological staining (Hematoxylin-Eosin, Toluidine Blue, and Safranin-O/Fast Green staining).

Custom culture services
Entire experiments can be contracted to Articular Engineering , or culture protocols can be modified to your specifications. These services would cover the inclusion of any substance during the growth of the ARC™ tissue outside of the normal culture conditions, or changes in culture duration to produce tissue with more or less mature properties. ARC™ tissue can be produced from any viable cartilage sample supplied by the customer. Samples might be from research animals in a current study, a particular strain of animal, or a gene-manipulated animal. There also exists the possibility to grow ARC™ tissue on top of most any type of biocompatible scaffold material to produce an osteochondral tissue. Articular Engineering will provide basic consultation on its products to determine if they are right for your needs at no cost. However, designing experiments and interpreting the data which has been obtained in a meaningful way can be a difficult task. Articular Engineering offers consultation services from top researchers in the field of connective tissue biochemistry with many years of experience with ARC™ tissue and its analysis.

 

Consultation

Articular Engineering will provide basic consultation on its products to determine if they are right for your needs at no cost. However, designing experiments and interpreting the data which has been obtained in a meaningful way can be a difficult task. Articular Engineering offers consultation services from top researchers in the field of connective tissue biochemistry with many years of experience with ARC™ tissue and its analysis.

 

 

 

 

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